Assessing health-related quality of life of Chinese population using CQ-11D

Purpose This study aimed to assess the health-related quality of life (HRQoL) of the Chinese population by using the Chinese medicine quality of life-11 dimensions (CQ-11D) questionnaire and to identify factors associated with HRQoL. Methods The data was derived from a survey conducted by the Institute of Pharmacoeconomics Evaluation at Beijing University of Chinese Medicine on the quality of life of the Chinese population. The sex and age of respondents were considered through quota sampling. Demographic, socioeconomic, and health indicators were collected using the structured questionnaire. We performed bivariate analyses first to examine the associations between the above factors and the HRQoL of respondents measured by the CQ-11D. Multivariate linear regression and ordinal logistic regression models were established to analyze the factors (demographic, socioeconomic, and health indicators) differences in HRQoL, as well as the risk of each group reporting problems across the 11 dimensions of CQ-11D. Results From February 2021 to November 2022, a total of 7,604 respondents were involved and 7,498 respondents were included. The sample approximated the general adult Chinese population in terms of age, sex, and district of residence, and each geographic distribution ranged from 9.71 to 25.54%. Of the respondents, 45.84% were male, and 89.82% were Han ethnicity. The mean utility score ranged from 0.796 to 0.921 as age increased. According to the respondents, most health problems were identified in the PL (fatigue) (70.16%) and SM (quality of sleep) (63.63%) dimensions. The CQ-11D index scores varied with the demographic and socioeconomic characteristics of respondents, except for ethnicity (p > 0.05) and income (p > 0.05). The multivariate analysis revealed significant negative associations between health utility scores and various factors. These factors include sex (female), age over 65, belonging to ethnic minorities, rural household registration, being widowed or divorced, having a primary school education or below, being a student or unemployed, having a low income of 0–1,300, engaging in smoking or drinking, limited participation in physical activities, experiencing changes in self-perceived health status compared to the previous year, and having chronic diseases. The odds of respondents reporting problems in 11 dimensions varied among different socio-demographic groups. Conclusions This study reports the first Chinese population norms for the CQ-11D derived using a representative sample of the Chinese general population. Self-reported health status measured by the CQ-11D varies among different socio-economic groups. In addition to participation a physical activity and the presence of chronic disease, smoking and drinking also significantly influence HRQoL. Supplementary Information The online version contains supplementary material available at 10.1186/s12955-024-02250-1


Introduction
Quality of life ( QoL ) is defined as "an individual's perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards, and concerns" [1].QoL includes solving complex, multi-factor relationships, covering a wide range of economic, socio-cultural, and lifestyle factors.With the integration of quality of life (QoL) and medical practice, the concept of Health-Related Quality of Life (HRQoL) has emerged [2].The term "Health-Related Quality of Life" (HRQoL) is used to define an individual's specific perception of health or to solely represent the utility associated with health conditions [3,4], which is a subset of overall quality of life (QoL).QoL measures are valuable for clinical studies for several reasons, which was used to quantify the impact of a condition and to compare the effects of disease or used to evaluate changes resulting from therapeutic intervention or the course of disease [5].Besides, QoL measures are necessary as a central component of cost-utility analysis (CUA), which has been widely used in health technology assessment and health policy decisions [6,7].
Over the past few decades, several HRQoL assessment instruments have been developed.Generic preference-based measures (GPBMs) such as the EuroQol five-dimension (EQ-5D) [8] and the Short Form sixdimension (SF-6D) survey [9][10][11] have become widely accepted in health utility studies.The EQ-5D has been developed in 2 versions with the same descriptive system and comprises five dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression [12,13].The health state classification system of SF-6Dv2 comprises six dimensions: physical functioning, role limitation, social functioning, pain, mental health, and vitality [14,15].Most of the GPBMs were developed in Europe and North America, and are often translated into other languages to use in many non-English speaking countries [16,17].However, health is a culturally related concept, and health evaluation indicators formulated in the Western cultural environment may not include Chinese cultural views on health [18].GPBMs focus on general health status, including physical, functional, and emotional domains.Currently, previous studies have carried out the construction of Chinese population norms based on the EQ-5D and SF-6D [19][20][21][22][23][24][25].The assessment instruments, EQ-5D-5 L and SF-6D, which have been widely used and developed, particularly based on foreign populations, have been found to exhibit ceiling and floor effects when measuring HRQoL [29][30][31].
The CQ-11D is a measurement tool developed specifically for the Chinese population to assess the quality of life [26,27].It is primarily used for evaluating the health utility of Traditional Chinese Medicine interventions as well as the general population's quality of life.The development of CQ-11D is based on the World Health Organization's (WHO) concept of quality of life and is guided by principles rooted in traditional Chinese medicine theory and the Chinese perspective on health.The theoretical and methodological framework of CQ-11D draws upon the domestic and international quality of life instruments and health utility scoring systems.Through a combination of literature research, Delphi method expert consultation, and Discrete Choice Experiment with Time Trade-Off (DCE TTO ) surveys, the items of the instrument have been identified and a corresponding health utility scoring system has been established.Existing research has confirmed the feasibility and good reliability and validity of the CQ-11D instrument [28].
In comparison, the CQ-11D instrument encompasses a greater number of dimensions and more comprehensive categories, offering a broader range of health utility measurements and more comprehensive results.Research has indicated a high level of consistency in the measurement results among these three instruments.Furthermore, the CQ-11D instrument demonstrates higher sensitivity in assessing certain chronic conditions such as hypertension and chronic gastritis [32].Based on these considerations, this research utilizes the CQ-11D instrument to conduct a comprehensive investigation of the target population to accurately reflect the health preferences and characteristics of the Chinese population.
It is important to note that population health surveys provide comprehensive information about the overall health status of residents as well as longitudinal trends, in addition to supporting the decision-making process in the healthcare field with empirical evidence [21].Many nations and regions have engaged in extensive research and published population norm data to enhance the utilization of health utility value data pertaining to specific populations in relevant studies.For example, notable contributions in this field have been made by countries such as Japan [33], Brazil [34], and Portugal [35].Population norms data can be used to compare profiles for patients with particular conditions with data for the average person in the general population from a similar age and sex group [36].Apart from its utility in capturing disease-specific health states, it can also serve as a comparative tool for assessing the health profiles of patients within subgroups sharing similar age and sex characteristics [37].Other countries have calculated normative utility scores using the EQ-5D and showed differences between sex, age, education, and other factors [38][39][40][41].
Our study aimed to provide population norms for HRQoL in China, based on the CQ-11D questionnaire.In addition, the multiple linear regression model and ordinal logistic regression model were used to explore the association of factors (demographic, socioeconomic, and health indicators) on HRQoL and the differences in 11 dimensions, respectively.

Study design and data collection
Data used in the study was obtained from the quality of life of the Chinese population survey based on the CQ-11D questionnaire, which was conducted by the Institute of Pharmacoeconomics Evaluation of Beijing University of Chinese Medicine [28,32].The survey period was from February 2021 to November 2022.To investigate the representativeness of the sample, quota sampling was used in the survey.Quotas were used to account for sex and age group, covering seven districts across the country, and strict training and questionnaire quality control was carried out (details of the survey design have been published [28,32]).The survey area covered all major cities in seven sub-regions of China, covering seven geographical divisions North China, Northeast China, East China, Central China, South China, Southwest China, and Northwest China.Recruited respondents by posting recruitment advertisements in a way that was convenient for the interviewer.Recruitment was conducted in publicly accessible places (Parks, shops, streets, and university campuses) and private areas (respondents' residences).A general representative population in China was investigated using one-on-one and face-to-face questionnaire interviews.The main steps of the first survey which was conducted from February 2021 to November 2022 were as follows [28]: The respondents were screened into the research and informed consent; the respondent completed the CQ-11D questionnaire; the respondents completed the DCE TTO tasks.In addition, after completing the DCE TTO tasks, respondents were asked to self-assess the difficulty of understanding and answering these tasks according to a 5-point Likert scale ranging from very easy to very difficult; The respondents answered the background information questionnaire (including the demographic characteristics, socioeconomic status, and health indicator), the EQ-5D-3 L and the SF-6D questionnaires; Recorded the time for the respondent to complete the survey; Checked whether the questionnaire was clear and complete.The second survey was carried out from February to November 2022, including three different survey parts [32]: The respondents were screened into the research and informed consent; The respondents answered the demographic characteristics, socioeconomic status, and health indicator questions; The respondents completed the CQ-11D, EQ-5D-5 L, and SF-6D, respectively.All investigations were conducted with the informed consent of the subjects and with Ethics Committee approval (the ethics committee of the Beijing University of Chinese Medicine, Approval number: 2021BZYLL03012).
For this study, data collected in the background information (the demographic characteristics, socioeconomic status, and health indicators) and CQ-11D questionnaire parts of the survey were utilized.

Health-related quality of life measured with the CQ-11D
CQ-11D contains 11 items: XD (movement and selfcare), SY (appetite), DB (stool), SM (quality of sleep), JS (spirit, including being alive, energetic, and focused), TY (dizziness, including feeling dizzy in the mind, with eyes closed for minor cases, or spinning in front of the scene in serious cases, inability to stand), XH (palpitations, or feeling restless), TT (pain), PL (fatigue), FZ (irritability), JL (anxiety, worried, anxious, nervous, restless), and depression (frustrated, lack of interest in doing things, no fun, low energy) [27].According to the unity between the body and the Shen (Spirit) theoretical of Chinese medicine, the first 8 dimensions are defined as body dimension (XING) while the last 3 dimensions are defined as Shen dimension (SHEN), as shown in Appendix 1.The health state for each item is categorized into 4 levels of severity (no, slight/occasionally, often, severe), allowing for the description of 4 11 (i.e., 4,194,304) different health states.The health utility value is calculated based on the item coefficients in the health utility scoring system, with a measurable range of -0.868 to 1.The CQ-11D utility value set can be found in Appendix 1.

Demographic and health-related variables
Previous studies have shown that there are differences in HRQol among demographic characteristics and socioeconomic status variables [23][24][25].Demographic characteristics and socioeconomic status including age, sex, level of education, marital status, ethnicity, occupation, household registration, income per month, and geographical division were collected according to the structured questionnaire.Moreover, lifestyle habits are associated with chronic diseases and may affect quality of life.The interview also collected health indicators on the frequency of participation in sports exercise or fitness activities, drinking, smoking, presence of chronic diseases, and changes in self-perceived health status compared to the previous year.

Statistical analysis
Demographic and health-related variables were analyzed by estimating mean values and standard deviations (SD) for continuous variables, frequencies, and proportions for categorical variables.We first conducted bivariate analyses to investigate the relationships between the aforementioned factors and the HRQoL of the respondents, as measured by the CQ-11D.Those utilities were compared among the respondents with different characteristics using non-parametric tests (Wilcoxon tests for two categories or Kruskal-Wallis tests for more than two categories) to examine differences in CQ-11D index scores of the respondents because the distribution of data was skewed.The percentage of people reporting any problem in each dimension was calculated and X 2 tests were performed to determine the statistical significance of the difference between groups in the percentage of reported any problems.The results were presented by sex and age groups.
We used multiple linear regression to examine the associations of socio-demographic characteristics with the CQ-11D index scores.Based on prior knowledge [42][43][44], covariates included age, sex, education level, marital status, ethnicity, occupation, household registration, income, geographical division, frequency of exercise, smoking behaviors, and presence of chronic conditions.We added drinking behaviors and changes in self-perceived health status compared to the previous year, which may also affect the HRQoL.In addition, ordinal logistic regression was developed with the 11 health dimensions as dependent variables (1 = no, 2 = slight/ occasionally, 3 = often, 4 = severe).Dummy variables were created for all of the independent variables in the modeling.The statistical analyses were carried out using the STATA 16 SE version.Statistical significance was set at 0.05 using two-sided tests.

Characteristics of respondents
From February 2021 to November 2022, a total of 7,604 respondents were involved, of which 106 interviews were excluded because the respondents did not complete the whole interview (N = 67), or the interviews did not meet the inclusion criteria (N = 5), or answered with logical inconsistencies (N = 17), or the interview took less than 5 min (N = 17).Finally, a total of 7,498 respondents were included.
The sample relative approximate to the general adult Chinese population in terms of age, sex, ethnicity, and district of residence, each geographic distribution ranged from 9.71 to 25.54% (compared with Communiqué of the Seventh National Population Census and China Statistical Yearbook of 2023 in Table 1, and see Table 2 for details).Of the respondents, 45.84% were men and 54.16% were women.About 89.82% of the respondents were Han ethnicity.And 62.34% of respondents were married and 32.24% were unmarried.52.28% of respondents were rural householding registration.About 20% of the respondents earn less than 1,300 CNY per month.A considerable proportion of the population possesses a higher level of education, with nearly 50% holding a university degree, while approximately 10% have completed only primary-level education.50.12% of respondents were employed and 8.58% were unemployed.About 40% of respondents reported the presence of chronic conditions.More than 70% of respondents reported participating in physical activities frequently or occasionally.74.58% of respondents were non-smokers and 53.77% were non-drinkers (Table 2).with a university degree education had higher CQ-11D index scores (0.915).In total, according to the responses of the individual CQ-11D dimensions, most health problems were identified in the PL (70.16%) and SM (63.63%) dimensions (Fig. 1).The percentage of "non-problem" were: 90.29% for XD, 53.03% for SY, 44.25% for DB, 36.37% for SM, 42.34% for JS, 50.85% for TY, 59.91% for XH, 52.64% for TT, 29.85% for PL, 40.72% for FZ, and 45.00% for JL.The percentage of reported problems for each level CQ-11D dimension for sex and age groups (Tables 3 and 4, and Fig. 2).The XING dimensions (XD, SM, DB, TY, SY, JS, TT, and XH) were relatively low percentages of any health problem in the younger age group, which increased with increasing age.The percentage of SHEN dimensions (PL, FZ, and JL) that reported any problems remained at a high level of about 45%∼75% across all age groups.The percentage of respondents who reported any problems in the PL dimension was higher in the 15 ∼ 24, 45 ∼ 54, and 75 + age groups.The proportion of participants who indicated difficulties in the FZ dimension and JL dimension was considerable, with a consistently high level of constraints (> 60%), which remained relatively steady across various age cohorts.We found significant differences between male and female respondents in every health dimension, except for the XD dimension (Table 3).For male respondents, there was a sharp increase in the age groups of 65 to 75 + for all health dimensions.This sharp increase was observed among female respondents in the age groups of 55 ∼ 64 to 65 ∼ 74.Once female respondents reached 75 + years old, the percentage of any problem in dimensions of SM, TT, and XH decreased.In general, a higher percentage of female respondents than males reported any problem across all dimensions.

Multivariable regression
Table 5 shows the results of multivariate analysis on socio-demographic characteristics and health-relative variables.The sex (female), older than 65 age, ethnicity of non-Han, being widowed or divorced, primary education level or below, household registration (rural), students or unemployed, smoking (occasionally, frequent, or former smoker), drinking (occasionally, frequent, or former drinker), physical activity(occasionally, never, or uncertain), changes self-perceived health status compared to the previous year (improved, worsened, or uncertain), and presence of chronic diseases were negative association with health utility scores and both significant.The Fig. 1 Frequencies of having "any problems" (level 2-4) in the CQ-11D dimensions in the whole sample  North, Central, and West-north geographic divisions, rural household registration, retirement, and being married were negative but not significantly associated with HRQoL.Compared with a monthly income of less than 1300 CNY, when the monthly income increased to 1300 ∼ 13,000 CNY, there was a significant positive correlation with the health utility value.Respondents who had experienced marriage had higher odds of reporting problems both in the XING and SHEN dimensions, especially those who were divorced and widowed respondents (OR 1.26 ∼ 2.13).The odds of reporting health problems increased with educational attainment in 3 dimensions of SHEN dimensions (PL, FZ, and JL), with those who were High school/Junior college and university educated having an OR 1.25 1.35 compared with those with higher than primary school education.Compared with employed respondents, unemployed respondents had higher odds of reporting health problems in some dimensions of XING dimensions (XD, SY, DB, JS, and TY) and had lower odds of reporting health problems in PL.Retired respondents had higher odds of reporting health problems in some dimensions of XING dimensions (XD, DB, SM, and TT), which may be related to the older age of retired respondents compared with employed respondents.Among health indicators, occasionally/often smoking (OR 1.5524 ∼ 2.8399), occasionally/often drinking (OR 1.14 ∼ 2.8307), occasionally/never participated in physical activities (OR 1.25 ∼ 2.13), and worsened/ uncertain changes in self-perceived health status compared to the previous year (OR 1.47 ∼ 3.49) increase the odds of reporting problems in almost all of the dimensions.Compared to non-smokers, occasional smokers have some negative impact on XD, SY, DB, JS, TY, XH, TT, and PL dimensions, with an OR range of 1.23 to 2.83.Frequent smokers compared to non-smokers have negative impacts on XD, DB, XH, PL, and FZ dimensions,

Discussion
To the best of our knowledge, this study is the first to estimate population norms for the descriptive section of the CQ-11D questionnaire among a representative sample of China.Norms for the CQ-11D were obtained through the usage of a recently developed CQ-11D value set [28].
The CQ-11D is a life quality assessment standard developed based on the principles of traditional Chinese medicine.There exist disparities in the dimensional count between the CQ-11D instrument and the internationally recognized GPBMs such as EQ-5D-5 L and SF-6D.However, comparative studies have demonstrated consistency in the measurement outcomes of these three instruments [32].The CQ-11D captures aspects of Chinese culture and TCM theory that are not included in other GPBMs (such as appetite, stool, and dizziness).According to the value set of CQ-11D, the largest decrements in utility were observed in the dimensions of Action and life self-care (HD), Pain (TT), Anxiety or depression (JL), and Appetite (SY), which had a significant impact on utility values but were not fully captured by GPBMs [28].Therefore, the CQ-11D instrument can comprehensively reflect the health preferences and characteristics of the Chinese population, making it more culturally applicable.Overall, the population had a mean CQ-11D utility score of 0.897(SD: 0.142), which was between the health utility values of the Chinese population measured by EQ-5D (0.946) [20], EQ-5D (0.939) [21], SF-6Dv2 (0.827) [20], SF-6Dv2 (0.872) [21] in previous studies.Similarly, our findings align with other Chinese population norms, indicating a consistent trend.The XD dimension is the least reported of any problem.About 47% of respondents reported any problem and about 3% of respondents reported 3-4 level problems in the TT dimension.It is similar to the reported problem in the pain dimension of SF-6Dv2 in previous studies [20].The SHEN dimensions (PL, FZ, and JL) problem were more prevalent among the younger population, and similar findings in the EQ-5D-5 L of the Chinese norm indicated that the anxiety/depression problem was more prevalent in the younger population [23].The potential explanation lies in the fact that the younger generation is exposed to a faster-paced and more stressful urban lifestyle in comparison to the older generation.Subsequently, this may result in higher demands in areas such as employment and education for the younger cohort.Measures such as improving employment security and the employment environment may reduce the pressure on young people and improve their HRQol.Compared with males, females appear to be at an increased risk of reported problems of body and spirit, and relatively lower utilities, which has been similarly found in previous studies [21,23,[44][45][46].In addition, similar findings to other studies were that lower socio-demographic status was associated with poorer HRQoL, i.e. lower income [44], primary education [43], rural householding [47] and so on.
There are also some new findings in this study.The PL dimension was the most frequently reported any problem (2-4 level) and the SM dimension was the most  Ref.
Ref Ref.
Ethnic minorities

East China
Ref. Ref.
North China  Ref.
Occasional participation  frequently reported 3-4 level (often or severity) problem in our study.Sleep quality and appetite are two health behaviors that were strongly associated with HRQoL [25].A previous study indicated that sufficient sleep (7-8 h/day) was significantly associated with increased HRQoL [48].The SM and SY of coefficients of the CQ-11D utility value set were − 0.051∼−0.149,which had a greater impact on the CQ-11D index score.Some previous studies did not find that smoking and drinking had a significant influence on HRQoL [25,49].However, smoking and drinking have consistently been recognized as risk factors for numerous chronic diseases, and have also shown their influence on HRQoL in other countries [50,51].
The findings in this study confirmed that smoking and drinking behaviors influence on HRQoL of the Chinese population.Occasionally/often smoking (OR 1.55 ∼ 2.83) and occasionally/often drinking (OR 1.14 ∼ 2.83) increase the odds of reporting problems in almost all of the dimensions.Besides, compared to non-smokers, quit-smoking respondents had lower odds of reporting problems across all dimensions than those who still smoked, although it was not a significant improvement in CQ-11D index scores.Similar findings were found among respondents who quit drinking and those who still drink alcohol.This finding implies that supporting smokers and drinkers in quitting these behaviors will improve their HRQoL.Participation in physical activities was positively correlated with the health utility value, and that was better when participating in physical exercise regularly.Although occasional physical activity and non-physical activity have similar odds of reporting problems in all dimensions compared with regular physical activity, the former 's health utility value is better than the latter.Participating in physical activity, whether regularly or occasionally, is beneficial for CQ-11D index scores, with regular physical activity demonstrating a more pronounced improvement in both physical and mental well-being.Therefore, it is advocated that people reduce or quit smoking and drinking, and take more physical activity.This can reduce the risk of reporting problems in aspects of such as sleep, appetite, stool, palpitation, and fatigue, thereby improving their HRQoL.
This study is subject to several limitations that need to be acknowledged and addressed in future research.Firstly, in the sampling process, the sampling of sex and ethnicity was consistent with the proportions of the seventh population census.However, the sample proportions of some populations (15∼24 years, East China, high education level, and rural household registration) are slightly higher than the seventh population census, which may have a certain impact on the study (Table 1).Given that the health utility value tends to be higher among individuals with a younger age and a higher education Ref.
Ref level, and the impact of health utility value between rural and non-rural household registrations and East China and other Geographical divisions are relatively smaller, sampling bias may lead to inflated health utility values for the overall sample.Secondly, cross-sectional data could not reflect the impact of time factors on HRQoL in different populations in China.In terms of understanding the causal relationship between variables and controlling for unobserved heterogeneity, longitudinal data is needed [23,52].Thirdly, the data used in this study did not match the assumptions of homoscedasticity and normality of the estimation errors.However, some studies of the EQ-5D have utilized OLS [44,53,54], while others have compared different modeling techniques and recommended the use of OLS [44,55,56].Consequently, we chose to perform OLS regression analysis for this study as well.

Conclusions
This study reports the first Chinese population norms for the CQ-11D derived using a representative sample of the Chinese general population.Self-reported health status measured by the CQ-11D varies among different socioeconomic groups.In addition to participation in physical activity and the presence of chronic diseases, smoking, and drinking also significantly influence HRQoL.

Table 1
Compare the distribution of sociodemographic characteristics with the Chinese census Note a the data is sourced from the Seventh National Population Census of China in 2020 https://www.stats.gov.cn/sj/zxfb/202302/t20230203_1901085.html;b the data is sourced from the China Statistical Yearbook of 2023 https://www.stats.gov.cn/sj/ndsj/2023/indexch.htm Pan et al.Health and Quality of Life Outcomes (2024) 22:34

Table 2
CQ-11D index scores and demographic characteristics of all respondentsNote: a When calculating the proportion of chronic diseases in each category, the denominator is the entire population; b Such as myocardial infarction, coronary heart disease, congestive heart failure, and other cardiac diseases; c Such as chronic bronchitis or emphysema; d Rheumatoid arthritis, osteoarthritis, gouty arthritis 0.803(SD: 0.211) for arthritis, 0.750(SD: 0.265) for osteoporosis or primary osteoporosis, and 0.750 (SD: 0.259) cancer or malignant tumor (Table2).The mean utility score ranged from 0.921 ± 0.107 (age group 16 ∼ 24) to 0.796 ± 0.248 (age group 75+).Female respondents had lower CQ-11D scores (Mean 0.886, SD 0.150) than male respondents (Mean 0.910, SD 0.131) with the p-values < 0.001.The CQ-11D index scores varied with the demographic and socioeconomic characteristics of respondents, except for ethnicity (p > 0.05) and income (p > 0.05).The lower CQ-11D index scores were associated with older age, being female, being married or widowed, unemployment (including being retired), rural household registration, smoking, drinking, not exercising, lower income, and chronic disease conditions.Respondents in the Northeast region had the highest CQ-11D index scores among the seven geographic divisions.Respondents with primary level education or below had lower CQ-11D index scores (0.825) and those

Table 2
(continued) Pan et al.Health and Quality of Life Outcomes (2024) 22:34 Pan et al.Health and Quality of Life Outcomes

Table 3
Percentage of reported problems in 11 health dimensions of CQ-11D presented by sex and age group Pan et al.Health and Quality of Life Outcomes

Table 6
(OR 3.16 ∼ 10.17).After the age of 65 years, the odds of reporting problems in the XING dimensions (SY, DB, TY, XH, and TT) are significantly increased (OR 1.38 ∼ 1.73).Compared with ethnic Han respondents, minority ethic respondents had higher odds of reporting problems were higher in XD and SY dimensions (OR 1.21 ∼ 1.90) and lower in the PL and FZ dimensions (OR 0.79 ∼ 0.80).

Table 4
Percentage of reported any problems in 11 health dimensions of CQ-11D presented by sex and age group Frequencies of having "any problems" (level 2-4) in the CQ-11D dimensions presented by sex and age groups Pan et al.Health and Quality of Life Outcomes (2024) 22:34 with an OR range of 1.20 to 1.55.Former smokers compared to non-smokers have negative impacts on the XH dimension, with an OR of 1.35.It can be seen that the number of dimensions with negative impacts is former smokers < frequent smokers < occasional smokers.For drinkers, there were similar results.Compared to nondrinkers, occasional drinkers have some negative effect on DB, SM, JS, TY, XH, TT, PL, FZ, and JL dimensions, with an OR range of 1.14 to 1.43; Frequent drinkers have some negative effect on XD, SY, DB, SM, TY, XH, TT, PL, FZ and JL, with OR range of 1.29 to 2.11; former drinkers have some negative effect on DB, SM, JS, TT, PL and JL, with an OR range of 1.33 to 1.68.It can be seen that the number of dimensions with negative impacts is former drinkers < occasional drinkers < frequent drinkers.Respondents with chronic conditions had an Fig. 2

Table 5
Associations between characteristics and CQ-11D index scores 1.62 ∼ 4.23 for reporting problems across all dimensions, especially the XD dimension (OR = 4.23).

Table 6
Associations between characteristics and health problems reported in 11 dimensions